The 341st Infantry Regiment was organized at Camp Howze, Texas, on December 15, 1942, and trained with the 86th Infantry Division through Louisiana, Camp Livingston, Camp Cooke, and Camp Myles Standish before sailing from Boston on February 19, 1945. It landed in France on March 1 and entered Germany on March 27 as the division moved into the final Central Europe campaign. Near Weiden, the 86th relieved elements of the 8th Infantry Division, then crossed the Rhine at Eibelshausen on April 5. The 341st was briefly attached to the 82nd Airborne Division and then reinforced the 97th Infantry Division during the Sieg River assault from April 6 to April 9.
After returning to divisional control, the 341st joined the 86th Division's drive against the Ruhr pocket. On April 13 it moved motorized from Hilchenbach toward the Hagen stop line, and on April 14 captured Hagen as the 342nd pressed toward Hohenlimburg and the 343rd cleared the Lenne River flank. When the division resumed operations in Bavaria, the regiment attacked with the 342nd on April 24, reached Eichstatt and the Altmuhl River, and crossed on April 26. It followed the 342nd to the Danube, crossing during April 27-28 after the Ingolstadt passage had been forced.
In the last week of combat the 341st helped push the division beyond the Amper Canal and the Isar. On May 2 the 86th replaced the 343rd with the 341st in the forward drive to Haag while Task Force Pope reached the outskirts of Wasserburg before the advance stopped. The regiment returned to the United States in June, staged for the Pacific, reached the Philippines in September 1945, and was inactivated there on December 30, 1946.
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